Related Experiment Videos
Formulary conversion from glipizide to glyburide: a cost-minimization analysis
1Bronx Municipal Hospital, NY 10461, USA.
Hospital Pharmacy
|June 1, 1995
Summary
Switching from glipizide to glyburide, an oral hypoglycemic agent, saved costs without impacting glycemic control or safety. This cost-saving strategy proved successful and became a model for other pharmacies.
Area of Science:
- Pharmacoeconomics
- Clinical Pharmacy
- Internal Medicine
Background:
- Hospitals face economic pressures requiring cost-saving strategies.
- Formulary substitution is a common approach to reduce medication expenses.
Purpose of the Study:
- To analyze the cost-minimization of substituting glyburide for glipizide.
- To evaluate the impact on glycemic control, patient safety, and overall costs.
Main Methods:
- A cost-minimization analysis was conducted.
- Prescription records of 76 patients were reviewed.
- Glycemic control and adverse events were monitored over a 2-year period.
Main Results:
- Switching from glipizide (19 mg/day) to glyburide (10.2 mg/day) did not affect glycemic control.
- A subset of 33 elderly patients had only three drug-related adverse events.
- A 51% reduction in oral hypoglycemic agent expenditures was achieved.
Conclusions:
- Formulary substitution of glyburide for glipizide is a successful cost-saving strategy.
- The program demonstrated efficacy in maintaining glycemic control and safety.
- This model can be adopted by other municipal outpatient pharmacies.