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Updated: Aug 10, 2026

Severe Burn Injury in a Swine Model for Clinical Dressing Assessment
Published on: November 6, 2018
[Change in serotonin content in burns]
Abstract:
Serotonin in blood, in burnt skin and burn blister fluid was studied fluorimetrically in 90 patients during different periods of burn disease. Burn disease was found to be accompanied with a considerable reduction of serotonin level in patients' blood, its increased content in burnt skin and its appearance in the blisters fluid. There is a direct correlation between the burn gravity and the rate of serotonin level reduction in blood. The data obtained allow a suggestion that a decreased serotonin content in blood is related with its accumulation in burnt skin and appearance in the blister fluid.
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