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Inhalation anthrax in a home craftsman

S C Suffin, W H Carnes, A F Kaufmann

    Human Pathology
    |September 1, 1978
    PubMed

    Insights

    This case report details a rare instance of inhalation anthrax complicated by subarachnoid hemorrhage. The infection resulted from simultaneous exposure to two distinct Bacillus anthracis strains from animal-origin yarn.

    Area of Science:

    • Medical Microbiology
    • Infectious Diseases
    • Neurology

    Background:

    • Anthrax is a serious infectious disease caused by Bacillus anthracis.
    • Inhalation anthrax is the most lethal form, often associated with high mortality rates.
    • Subarachnoid hemorrhage is bleeding in the space between the brain and the tissues covering the brain.

    Observation:

    • A home craftsman developed inhalation anthrax.
    • The patient presented with complicating subarachnoid hemorrhage.
    • The infection was attributed to simultaneous infection with two capsular biotypes of Bacillus anthracis.

    Findings:

    • The two Bacillus anthracis biotypes exhibited different virulence in mouse models.
    • This dual-biotype infection led to a rare clinical presentation of anthrax with neurological complications.
    • The source of infection was identified as imported animal-origin yarn.

    Implications:

    • Highlights the potential for rare and severe complications in anthrax cases.
    • Underscores the importance of considering unusual infectious agents and co-infections.
    • Emphasizes the need for vigilance regarding zoonotic diseases transmitted through animal products.

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