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Criteria-based antimicrobial i.v. to oral conversion program.

A U Okpara1, J J Maswoswe, K Stewart

  • 1Lyndon B. Johnson General Hospital, Houston, TX 77026, USA.

Formulary (Cleveland, Ohio)
|May 8, 1995
PubMed
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A new IV to oral antimicrobial conversion program in a teaching hospital successfully transitioned 78 patients in two months. This initiative improved patient outcomes and physician prescribing while achieving significant cost savings.

Area of Science:

  • Pharmacology
  • Hospital Administration
  • Infectious Disease Management

Background:

  • Parenteral antimicrobial use requires careful monitoring for appropriateness.
  • Transitioning from intravenous (IV) to oral antimicrobial therapy can optimize patient care and reduce costs.

Purpose of the Study:

  • To implement and evaluate a criteria-based IV to oral antimicrobial conversion program.
  • To monitor antimicrobial prescribing, facilitate IV to oral therapy transition, and control healthcare costs.

Main Methods:

  • Collaborative development involving multiple hospital departments and the P & T Committee.
  • Establishment of a criteria-based program for select antimicrobials in a 580-bed county teaching hospital.
  • Physician education on appropriate parenteral antimicrobial prescribing.

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Main Results:

  • 78 patients were converted from IV to oral antimicrobial administration within the first two months.
  • Estimated cost savings of $12,935 were achieved.
  • Physician acceptance of interventions was high (84.6%), with all converted patients successfully treated with oral agents.

Conclusions:

  • The IV to oral conversion program effectively reduced costs and improved patient outcomes.
  • The program positively influenced physician prescribing habits regarding antimicrobial therapy.
  • This initiative demonstrates a successful model for antimicrobial stewardship in a hospital setting.