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Dosing guidelines for foscarnet and trimetrexate
J M Wooten1, K Chase, M C O'Connor
1Trinity Lutheran Hospital, Kansas City, MO, USA.
Abstract:
The P & T Committee at Trinity Lutheran Hospital, a 320-bed, community/teaching hospital in Kansas City, MO, has developed dosing and monitoring guidelines for foscarnet sodium (Foscavir) and trimetrexate glucuronate (Neutrexin)--two drugs used to treat patients with opportunistic infections associated with the human immunodeficiency virus (HIV). Presented in this Experience Brief is a short discussion of these drugs, the rationale for guideline development, and the actual dosing and monitoring protocols devised.
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