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Updated: Aug 14, 2026

An Orthotopic Mouse Model of Anaplastic Thyroid Carcinoma
Published on: April 17, 2013
[Variants in the course of papillary carcinoma of the thyroid gland (clinico-morphologic analysis)]
Abstract:
A clinico-morphological analysis of 157 cases of papillary cancer of the thyroid is made. Depending on the presence and time of appearance of regional metastases three groups of patients are distinguished: I -- regional metastases are the first clinical manifestation of the lesion (87 patients); II -- the lesion starts with the appearance of a node in the gland, regional metastases develop later (50 patients); III -- thyroid tumor without regional metastases (20 patients). The groups sungled out differ reliably in the rate of tumor growth and prognosis. The first group proved to be most favourable with respect to prognosis. A five-year survival in patients of the first group was noted in 92 +/- 3.3%, while 84 +/- 7.4% of patients survived for 10 years and longer. There were no essential differences in the morphological signs in the concerned clinical groups of papillary cancer of the thyroid.
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