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Updated: Aug 12, 2026

A Detailed Protocol for Physiological Parameters Acquisition and Analysis in Neurosurgical Critical Patients
Published on: October 17, 2017
[Comparative study of intracerebral and cerebrospinal fluid pressure in neurosurgical clinical practice]
Abstract:
Comparative measurements of cerebrospinal fluid pressure(CSPF), total local intrabrain pressure (IBP) and interstitial fluid pressure(ISFP) have been made in 32 neurosurgical patients in the postoperative period. The obtained data prove that IBP is almost twice higher than ISFP and 1.5 times higher than CSFP. The data of this study show that no direct hydrostatic relation exists between the cerebrospinal fluid and the interstitial fluid. The reasons of "negative" values of ISFP are also discussed. The intracranial pressure is to be considred as a combination of selective mechanical pressures of the main intracranial components. Therefore a more precise term "intracranial pressures" is suggested.
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