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An evaluation of antihypertensive prescribing practices
D A Knapp1, R J Michocki, J P Richardson
1Center on Drugs and Public Policy, and Schools of Pharmacy and Medicine, University of Maryland, Baltimore.
US physicians generally follow hypertension management guidelines. Continuing education should focus on optimal use of alpha 2-agonists and cost-effective once-daily dosing of antihypertensives.
Area of Science:
- Cardiology
- Pharmacoeconomics
- Internal Medicine
Background:
- Hypertension management requires adherence to guidelines and cost-effective prescribing.
- Physician prescribing patterns for hypertension need evaluation against established standards.
- Pharmacoeconomic considerations are crucial for long-term patient management.
Purpose of the Study:
- To assess US physicians' management of hypertension, including drug prescribing practices.
- To compare physician prescribing patterns with National Institutes of Health (NIH) guidelines.
- To analyze the pharmacoeconomics of prescribed antihypertensive medications.
Main Methods:
- Utilized a 1991 national US database derived from physician-patient encounter forms.
- Evaluated diagnostic/screening services, patient counseling, drug prescribing, and follow-up care.
- Compared prescribed antihypertensive drugs based on NIH guidelines and cost-effectiveness.
Main Results:
- Physicians largely adhered to NIH guidelines for hypertension care.
- A need for continuing medical education was identified regarding alpha 2-agonists' optimal use.
- Specific once-daily formulations of hydrochlorothiazide, chlorthalidone, and atenolol were found to be more cost-effective.
Conclusions:
- US physicians demonstrate general compliance with hypertension management guidelines.
- Targeted education is needed for appropriate use of centrally acting alpha 2-agonists.
- Cost-effective once-daily antihypertensive options exist, particularly hydrochlorothiazide, chlorthalidone, and atenolol.
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