Related Experiment Video
Updated: Oct 7, 2026

Assessment of Pulmonary Capillary Blood Volume, Membrane Diffusing Capacity, and Intrapulmonary Arteriovenous Anastomoses During Exercise
Published on: February 20, 2017
A comparison of two oxygen transfer strategies: Bentley Univox and the Bard HF 5000
1Division of Cardiothoracic Surgery, Albert Einstein Medical Center, Philadelphia, Pennsylvania.
Abstract:
The purpose of this study was to evaluate the oxygen transfer performance of two membrane oxygenators: Bentley Univox and the Bard HF 5000. This evaluation was based on the comparison between: (1) the oxygen transfer slope; (2) the gas phase-arterial oxygen gradients; (3) the degree of blood shunting; (4) the maximum oxygen transfer; and (5) the diffusing capacity calculated for each membrane. The data were examined at both absolute values and relative to each device's membrane surface area. In absolute terms, the HF 5000 performed better than the Univox in each category. However, when surface area was taken into account, the Univox was clearly more efficient with regard to oxygen transfer. We conclude from this evaluation that the Univox does not offer a satisfactory oxygen transfer 'buffer' for larger, more metabolically active patients (297 ml/min for the Univox and 447 ml/min for the HF 5000). The trade-offs that were made between design and performance features, with the Univox, were unacceptable.
Related Concept Videos
Oxygen Delivering System I: Nasal Cannula and Face Mask
Nasal Cannula
A nasal cannula is a lightweight tube split at one end into two prongs and placed in the nostrils. It is typically used to deliver low to medium levels of oxygen.
Suggested flow rate: The suggested flow rate for a nasal cannula typically ranges between 1 and 6 L/min.
Oxygen percentage setting:...
Oxygen Delivering System II: Venturi Mask and Transtracheal Oxygen
Venturi Mask
The Venturi mask, named after the Venturi effect, is designed to deliver precise oxygen concentrations. It consists of a large tube with an oxygen inlet that narrows down, causing a pressure drop that pulls air in through adjustable side ports. The mask is a lightweight,...
Oxygen Delivering System III: Tracheostomy and T-piece
Tracheostomy
A tracheostomy is a surgically created opening (stoma) in the anterior part of the trachea. It is used to establish a patient airway, bypass an upper airway obstruction, simplify the removal of secretions, permit long-term...
Extracorporeal Removal of Drugs: Hemoperfusion and Hemofiltration
Bioreactor Controls-II

