Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

The technique of inverse ratio ventilation. Steps to improve oxygenation and decrease dead space ventilation.

M Johnson1, R D Cane

  • 1University of South Florida College of Medicine, Tampa.

The Journal of Critical Illness
|May 8, 1992
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Body dysmorphic disorder in patients with anxiety disorders and major depression: a comorbidity study.

The American journal of psychiatry·1995
Same author

Assessment of hibernating myocardium by dobutamine stimulation in a canine model.

Journal of the American College of Cardiology·1995
Same author

Essential thrombocytosis: underemphasized cause of large-vessel thrombosis.

Journal of vascular surgery·1995
Same author

Healing determinants in older people with leg ulcers.

Research in nursing & health·1995
Same author

Selective tumorigenesis in non-parenchymal liver epithelial cell lines by hepatocyte growth factor transfection.

Cancer letters·1995
Same author

Osteogenic protein-1 induces dendritic growth in rat sympathetic neurons.

Neuron·1995
Same journal

Using transcutaneous cardiac pacing to best advantage: How to ensure successful capture and avoid complications.

The Journal of critical illness·2019
Same journal

Techniques for noninvasive diagnosis of lower respiratory tract infections. Which tests to order, when to consider invasive procedures.

The Journal of critical illness·1995
Same journal

Choosing the right dialysis option for your critically ill patient. What's right for a hyperkalemic patient may be wrong for one with shock.

The Journal of critical illness·1995
Same journal

The technique of administering enteral nutrition. Practical pointers for ensuring correct placement, avoiding complications.

The Journal of critical illness·1995
Same journal

The technique of pericardiocentesis. When to perform it and how to minimize complications.

The Journal of critical illness·1995
Same journal

Treating intracerebral hemorrhage effectively in the ICU. The key steps: provide supportive care and determine the cause.

The Journal of critical illness·1995
See all related articles

Pressure-control inverse ratio ventilation (IRV) may improve oxygenation in acute lung disease by prolonging inspiratory time. However, patients cannot breathe spontaneously, and optimal settings balance oxygenation with hemodynamic stability.

Area of Science:

  • Critical Care Medicine
  • Respiratory Physiology
  • Mechanical Ventilation

Background:

  • Inverse Ratio Ventilation (IRV) is a ventilatory technique characterized by a prolonged inspiratory time.
  • Pressure-control IRV theoretically allows for improved ventilation and oxygenation at lower peak airway and end-expiratory pressures.
  • This may reduce ventilator-induced lung injury by minimizing shearing forces.

Purpose of the Study:

  • To discuss the application of pressure-control IRV in patients with acute lung injury.
  • To highlight the potential benefits and limitations of this ventilatory strategy.

Main Methods:

  • The abstract discusses the theoretical underpinnings and clinical considerations of pressure-control IRV.
  • It emphasizes the importance of selecting appropriate inspiratory-to-expiratory ratios.

Related Experiment Videos

Main Results:

  • Pressure-control IRV may be beneficial for patients with acute lung disease, low lung compliance, microatelectasis, and intrapulmonary shunting.
  • A key limitation is the inability of patients to breathe spontaneously during IRV.
  • Optimizing the inspiratory-to-expiratory ratio is crucial to improve oxygenation without compromising cardiac output.

Conclusions:

  • Pressure-control IRV is a potential ventilatory strategy for specific acute lung conditions.
  • Careful consideration of the inspiratory-to-expiratory ratio is necessary to balance oxygenation benefits with potential hemodynamic compromise.
  • Further research or clinical trials may be needed to fully establish its role and optimize its use.