Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Transmyocardial laser revascularization: a review.

M Mirhoseini1, S Shelgikar, M M Cayton

  • 1Heart and Lung Institute of Wisconsin, Milwaukee.

Journal of Clinical Laser Medicine & Surgery
|February 1, 1993
PubMed
Summary

Transmyocardial laser revascularization creates channels in the heart for perfusion, offering a potential new treatment for ischemic heart disease patients not eligible for standard therapies.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Laser revascularization of ischemic skeletal muscle.

The Journal of surgical research·2003
Same author

Transmyocardial laser revascularization in the patient with unmanageable unstable angina.

The Annals of thoracic surgery·1999
Same author

Transmyocardial laser revascularization: historical background and future directions.

Journal of clinical laser medicine & surgery·1998
Same author

Transmyocardial laser revascularization in allograft coronary artery disease.

The Annals of thoracic surgery·1998
Same author

A clinician's overview of laser systems for cardiovascular applications.

Journal of clinical laser medicine & surgery·1993
Same author

Technical considerations and factors that influence the outcome of laser-assisted angioplasty.

Journal of clinical laser medicine & surgery·1991

Area of Science:

  • Cardiovascular Surgery
  • Interventional Cardiology

Background:

  • Ischemic heart disease (IHD) management has advanced with new surgical, medication, and catheter-based treatments.
  • Despite progress, some patients with myocardial ischemia remain ineligible for conventional therapies.
  • Transmyocardial laser revascularization (TMLR) presents a potential alternative or adjunct treatment.

Purpose of the Study:

  • To evaluate the efficacy and safety of transmyocardial laser revascularization (TMLR) as a treatment for patients with ischemic heart disease.
  • To assess the potential benefits of TMLR for patients who are not candidates for conventional therapies.

Main Methods:

  • TMLR involves creating channels through the epicardium, left ventricle, and endocardium using a CO2 laser.
  • Perfusion is achieved via the left ventricular blood supply through these created channels.
  • Postoperative assessments included thallium stress tests and left ventriculography.

Main Results:

  • Postoperative tests confirmed that the channels created by TMLR remained patent.
  • The TMLR procedure demonstrated the ability to protect ischemic heart muscle.
  • Early clinical and experimental results suggest TMLR benefits a specific patient group.

Conclusions:

  • Transmyocardial laser revascularization is a promising therapeutic option for select patients with ischemic heart disease.
  • TMLR may serve as a viable adjunct or alternative to conventional treatments for refractory myocardial ischemia.
  • Further research into TMLR is warranted to define its role in managing ischemic heart disease.

Related Experiment Videos