Related Experiment Video
Updated: Aug 10, 2026

A Murine Model of Stent Implantation in the Carotid Artery for the Study of Restenosis
Published on: May 14, 2013
Coronary angioplasty in stenotic lesions adjacent to coronary aneurysms
1Minneapolis Heart Institute/Abbott Northwestern Hospital, MN 55407.
Insights
Coronary angioplasty effectively treats stenoses near coronary aneurysms, showing a high success rate and safety. This intervention offers a viable option for patients with complex coronary artery conditions.
Area of Science:
- Cardiovascular Medicine
- Interventional Cardiology
Background:
- Coronary aneurysms present unique challenges for treating adjacent stenoses.
- Percutaneous coronary intervention (PCI) is a common treatment for coronary artery disease.
Purpose of the Study:
- To evaluate the safety and efficacy of coronary angioplasty for stenoses adjacent to coronary aneurysms.
- To assess the outcomes of PCI in this specific patient subgroup.
Main Methods:
- Retrospective study of 25 patients undergoing coronary angioplasty for stenoses adjacent to coronary aneurysms.
- Analysis of procedural success, clinical outcomes, and long-term follow-up.
Main Results:
- High primary clinical success rate (96%) with significant reduction in stenosis and transstenotic gradient.
- Low incidence of major adverse events, with no embolic events or coronary artery rupture.
- 71% of patients remained asymptomatic at a mean follow-up of 7.7 months.
Conclusions:
- Coronary angioplasty is a safe and effective treatment for stenoses adjacent to coronary aneurysms.
- The procedure demonstrates a high primary success rate and favorable short-term outcomes in this challenging patient population.
Abstract:
The efficacy and safety of coronary angioplasty for stenoses adjacent to coronary aneurysms were studied in 25 patients (19 men and 6 women, mean age 62 +/- 11 years). The study represented 1.1% of patients undergoing coronary angioplasty during the study time period. The aneurysm diameter exceeded 1.8 +/- 0.2 times the normal artery diameter. Eleven (44%) of these aneurysms were localized in the left anterior descending, 3 (12%) in the circumflex and 11 (44%) in the right coronary artery. Percent diameter stenosis was reduced from 72 +/- 10% to 23 +/- 19%, and transstenotic gradient from 51 +/- 13 to 15 +/- 9 mmHg when measured. Clinical success (absence of pain on discharge without coronary bypass surgery, death, or infarction) was achieved in 24 (96%) patients. In one patient acute vessel closure occurred. No embolic events or coronary artery rupture occurred. Seventeen (71%) of the 24 successful patients remained asymptomatic at clinical follow-up (mean = 7.7 +/- 5.0 months). At late follow-up, one patient had sustained a myocardial infarction, two had elective bypass surgery, and two had successful repeat angioplasty. The data from this small patient population suggest that angioplasty for a stenosis adjacent to a coronary aneurysm can be performed safely with a high primary success rate.
More Related Videos
13:10Direct Re-implantation of Left Coronary Artery into the Aorta in Adults with Anomalous Origin of Left Coronary Artery from the Pulmonary Artery (ALCAPA)
Published on: April 24, 2017
06:39Novel Percutaneous Approach for Deployment of 3D Printed Coronary Stenosis Implants in Swine Models of Ischemic Heart Disease
Published on: February 18, 2020
Related Concept Videos
Coronary Artery Disease V: Interprofessional Care
Acute Coronary Syndrome IV: Interprofessional Care
Angina II: Classification
Angina IV: Management
Peripheral Artery Disease III: Interprofessional Care
Aneurysm III: Interprofessional Care