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Skeletal muscle for cardiac assistance
1Wayne State University, Detroit, Michigan.
Current Opinion in Cardiology
|April 1, 1991
Summary
Skeletal muscle is increasingly used for cardiac assistance. Recent advancements focus on the latissimus dorsi muscle for cardiomyoplasty and experimental pumping chambers, offering promising new support methods.
Area of Science:
- Biomedical Engineering
- Cardiovascular Surgery
- Regenerative Medicine
Background:
- Significant interest exists in utilizing skeletal muscle for cardiac assistance.
- The latissimus dorsi muscle is a key focus due to its conditioned, fatigue-resistant properties.
Purpose of the Study:
- To review recent developments in skeletal muscle use for cardiac assistance over the past 12 months.
- To highlight the applications of the latissimus dorsi muscle in cardiac support.
Main Methods:
- Review of recent literature and clinical applications.
- Analysis of experimental techniques involving skeletal muscle grafts.
Main Results:
- The latissimus dorsi muscle is proposed for cardiomyoplasty, separate pumping chambers, and alternative assist systems.
- Clinical application of cardiomyoplasty has been achieved.
Conclusions:
- While cardiomyoplasty is clinically established, other skeletal muscle-based cardiac assist methods are still experimental.
- These experimental techniques show promise for future cardiac support strategies.