Related Experiment Videos
[Coronary artherosclerosis, coronary thrombosis and myocardial infarction in autopsy cases (author's transl)]
Insights
This study analyzed coronary thrombosis and sclerosis autopsy data from 1951-1969. Coronary thrombi were more common in men and severe coronary sclerosis, with a higher incidence in the left coronary artery.
Area of Science:
- Cardiovascular Pathology
- Forensic Medicine
Context:
- Autopsy reports from the Pathological Institute Erfurt (1951-1969) were reviewed.
- Focus on coronary sclerosis and coronary thrombosis incidence and distribution.
Purpose:
- To analyze the frequency and distribution of coronary sclerosis and thrombosis by age and sex.
- To investigate the relationship between thrombus formation and severity of coronary sclerosis.
- To determine the location and characteristics of coronary thrombi.
Summary:
- Coronary sclerosis with thrombosis occurred in 3.97% of autopsies (4.93% men, 2.62% women).
- Thrombi were significantly more frequent in severe coronary sclerosis (8.96%) versus mild/moderate (1.39%).
- Males had a higher incidence of ischemic heart disease.
- Thrombi were more common in the left coronary artery (2.46%) than the right (1.51%).
- Non-obturating and fresh thrombi were more prevalent than obturating and organized thrombi.
- A decrease in coronary thrombosis relative frequency was observed with increasing age in both sexes.
Impact:
- Provides historical epidemiological data on coronary thrombosis and sclerosis.
- Highlights significant correlations between thrombus formation, sclerosis severity, sex, and coronary artery location.
- Contributes to understanding risk factors and pathological patterns of ischemic heart disease.
Abstract:
The autopsy reports of the Pathological Institute Erfurt of the period from 1.1. 1951 untile 31.12. 1969 were scored for cases of coronary sclerosis and coronary thrombosis and analysed concerning frequency and distribution of age and sex, resp. In 3.97 per cent of all autopsies (4.93 per cent of men, 2.62 per cent of women) a coronary sclerosis was present in combination with a coronary thrombosis. Coronary thrombi appeared more frequent in severe coronary sclerosis (8.96%) than in weak or moderately severe coronary sclerosis (1.39%). Males suffered significantly more frequent from these forms of icaemic heart disease. Coronary thrombi were found more frequently in the left coronary artery (2.46%) than in the right coronary (1.51%). This difference was significant. Non obturating thromboses were more frequent than obturating ones and those being in organization were rarer than fresh thromboses. In all cases a decrease of the relative frequency of the coronary thrombosis with increasing age in men and women is detected.