[Principles of therapy with antibiotics and chemotherapeutics]

Important aspects for the today therapy and prophylaxis with antibiotics/chemotherapeutics resp. are represented (choice of the antibiotic, treatment with antibiotic or sulphonamide, bacteriostatic or bactericidal activity, combination possibilities with examples). A strong indication for the application of chemotherapeutic agents is demanded. The necessity of careful sensitivity tests before instituting chemotherapy is emphasised. Reasons for the essentially economical application of drugs today are referred to. Especially is discussed the problem of transferable drug resistance, the resistance situation during therapy, and the problem of drug application outside medicine.