[The syndrome of ovarian hypoplasia]

The authors, on the basis of broad and endocrinological studies and of histological investigation of the ovaries, performed in 21 women, described an uniform disease picture which allowes to delimit ovarian hypoplastic syndrome out of a group of patients with ovarial insufficiency. This syndrome is characterized by primary or secondary amenorrhoea, normal height, weak development of secondary sexfeatures, and by small ovaries which have the oval or roller, more seldom ball-like or streaking form. The histological picture of the ovaries consist of fibrous stroma without generative elements or with a small number of primary follicles, but sometimes also with single growing Graaf's follicle. The excretion of estrogens is very low and in the case of gonadotrophins it increases.