[Comparative study of the immunologic effectiveness of the oral and subcutaneous methods of administering pertussis vaccine]

The authors present the results of study of humoral immunity in rabbits after oral and subcutaneous immunization with pertussis vaccine. There was an increase in agglutinin titre and of the protective properties of the serum both after the oral administration of the vaccine according to two different schemes and after the subcutaneous immunization. However, rabbits immunized orally displayed a more prolonged (150-day) persistence of agglutinin titres, as well as of preventive and protective activity of the sera than rabbits immunized subcutaneoulsy.