Ocular manifestations of congenital rubella

Ocular disease is a major component of the congenital rubella syndrome (CRS). Interest in this condition has been renewed after identification of a spectrum of delayed manifestations and the realization that sporadic cases of CRS will continue to occur despite vaccination programs due to reinfection in the immune patient. Work is continuing on strategies and planning of vaccination programs for disease prevention and control, refinements of diagnosis with particular emphasis on the prenatal diagnosis of fetal infection, and fundamental research into the pathogenic and immunologic mechanisms underlying CRS and its late manifestations.