Related Experiment Video
Updated: Aug 10, 2026

07:47
Experimental Human Pneumococcal Carriage
Published on: February 15, 2013
Implementing a policy for pneumococcal prophylaxis in a haematology unit after splenectomy
Quality in Health Care : QHC
|August 6, 1995
Summary
Splenectomy patients face high infection risks. A formal policy for pneumococcal immunisation and antibiotic prophylaxis significantly improved preventative care for these vulnerable individuals.
Area of Science:
- Hematology
- Infectious Diseases
- Public Health
Background:
- Splenectomy significantly increases the risk of overwhelming post-splenectomy infection (OPSI), particularly pneumococcal infections and sepsis.
- Patients undergoing splenectomy are 40 times more likely to develop severe infections and 17 times more likely to experience fatal sepsis.
- Preventative measures, including pneumococcal vaccination and antibiotic prophylaxis, can reduce the incidence of these life-threatening infections.
Purpose of the Study:
- To audit the effectiveness of a formal policy for pneumococcal immunisation and antibiotic prophylaxis in patients undergoing elective splenectomy.
- To assess the impact of implementing a standardized care protocol on preventative measures for post-splenectomy infection risk.
Main Methods:
- Retrospective analysis of patient case notes.
- Audit conducted in July 1993, evaluating data from patients who had undergone splenectomy.
- Comparison of prophylaxis rates before and after the implementation of a formal policy in June 1988.
Main Results:
- Before the policy (June 1988), only 24% of splenectomy patients received both pneumococcal immunisation and antibiotic prophylaxis.
- After policy implementation, 62% received immunisation and 86% received antibiotic prophylaxis or a fever-activated antibiotic supply.
- All but one of the 20 patients who had splenectomies after the policy was enacted received appropriate prophylaxis.
Conclusions:
- Establishing a formal, agreed-upon policy for pneumococcal prophylaxis in splenectomy patients demonstrably improved the quality of care.
- Standardized protocols are effective in increasing the uptake of essential preventative measures for high-risk patient groups.
- The policy led to a significant increase in the provision of immunisation and antibiotic prophylaxis for patients undergoing splenectomy.
More Related Videos
Related Concept Videos
Transmission-based Precautions II: Airborne and Protective Environment
Transmission-based precautions are for patients infected or suspected to be infected (or colonized) with organisms posing a significant risk to others. The transmission precautions include airborne and protective environment precautions.
Airborne precautions:
Use airborne precautions when treating patients known or suspected to have diseases that spread through the air—for example, tuberculosis or measles. These organisms are present in smaller droplets expelled by an infected person and...
Airborne precautions:
Use airborne precautions when treating patients known or suspected to have diseases that spread through the air—for example, tuberculosis or measles. These organisms are present in smaller droplets expelled by an infected person and...
Standard Precaution
Standard precautions are the minimum infection control safeguards used while caring for all patients, irrespective of their disease condition. They help prevent the spread of common infectious microorganisms to healthcare workers, patients, and visitors in all healthcare settings.
Hand hygiene is the most crucial means to prevent the transmission of disease. Employers are legally required to provide their workers with personal protective equipment (PPE) to minimize exposure or contact with...
Hand hygiene is the most crucial means to prevent the transmission of disease. Employers are legally required to provide their workers with personal protective equipment (PPE) to minimize exposure or contact with...
Pneumonia III: Complications and Assessment
Pneumonia poses the potential for numerous complications that warrant consideration. These complications include the following:
Pneumonia IV: Management
The treatment of pneumonia varies based on its severity and the causative pathogen. Here is a structured approach to managing pneumonia, integrating pharmaceutical and supportive care strategies.
Bacterial Pneumonia Treatment
For bacterial pneumonia, antibiotics serve as the cornerstone of therapy. Initial treatment often begins with empirical antibiotics, tailored to the anticipated causative organism and adjusted based on culture results. Key antibiotic choices include:
Bacterial Pneumonia Treatment
For bacterial pneumonia, antibiotics serve as the cornerstone of therapy. Initial treatment often begins with empirical antibiotics, tailored to the anticipated causative organism and adjusted based on culture results. Key antibiotic choices include:
Pneumonia V: Nursing management and Prevention
Nursing management of pneumonia involves promoting airway patency, facilitating rest and conserving energy, encouraging fluid intake, maintaining nutrition, and educating patients.
The nurse must practice strict medical asepsis and adhere to infection control guidelines to minimize healthcare-associated infections.
Enhance airway patency
Position the patient correctly to facilitate drainage of the affected lung segments. Manual or mechanical percussion and vibration can also be employed.
The nurse must practice strict medical asepsis and adhere to infection control guidelines to minimize healthcare-associated infections.
Enhance airway patency
Position the patient correctly to facilitate drainage of the affected lung segments. Manual or mechanical percussion and vibration can also be employed.
Pneumonia I: Introduction
Pneumonia is an infection of the lower respiratory tract that leads to inflammation of the lung parenchyma, often resulting in the accumulation of inflammatory exudate in the alveoli and airways. Unlike the watery, low-protein fluid exudate in pulmonary edema, the exudate in this case is a thick fluid rich in immune cells, proteins, and debris produced during infection and inflammation.This impairs gas exchange and can lead to consolidation of lung tissue. The infection may be caused by a...

