Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Two-sided assortative mating for a single locus.

S R Wilson

    Annals of Human Genetics
    |November 1, 1976
    PubMed
    Summary
    This summary is machine-generated.

    This study models two-sided assortative mating for human populations, analyzing gene frequency changes with two autosomal alleles and dominance. It establishes conditions for stable genetic polymorphism, offering a more realistic approach to population genetics.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Clinical impact of CEUS on non-characterizable observations and observations with intermediate probability of malignancy on CT/MRI in patients at risk for HCC.

    Abdominal radiology (New York)·2024
    Same author

    Continuing benefits of the Montreal Protocol and protection of the stratospheric ozone layer for human health and the environment.

    Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology·2024
    Same author

    Changes in tropospheric air quality related to the protection of stratospheric ozone in a changing climate.

    Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology·2023
    Same author

    Environmental effects of stratospheric ozone depletion, UV radiation, and interactions with climate change: UNEP Environmental Effects Assessment Panel, Update 2021.

    Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology·2022
    Same author

    Environmental effects of stratospheric ozone depletion, UV radiation, and interactions with climate change: UNEP Environmental Effects Assessment Panel, Update 2020.

    Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology·2021
    Same author

    Environmental effects of stratospheric ozone depletion, UV radiation and interactions with climate change: UNEP Environmental Effects Assessment Panel, update 2019.

    Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology·2020
    Same journal

    FIGLA Novel Variant c.385-9G>A Affects RNA Splicing in a Minigene Assay.

    Annals of human genetics·2026
    Same journal

    Epigenetic Shifts in MTNR1A, MTNR1B and Fn14 and Their Links to Preeclampsia Risk.

    Annals of human genetics·2026
    Same journal

    Hip Bone Marrow Adiposity as a Risk Factor for Alzheimer's Disease: Insights From Mendelian Randomization Analysis.

    Annals of human genetics·2026
    Same journal

    A Novel Biallelic REL Frameshift Variant p.(Tyr9Ilefs*2) Causing Immunodeficiency-92 With Profound c-Rel Deficiency.

    Annals of human genetics·2026
    Same journal

    Identification of PSMA4 as a Therapeutic Target for Atherosclerosis: A Comprehensive Multiomics Mendelian Randomization Analysis.

    Annals of human genetics·2026
    Same journal

    Genetic Insights Into Hypertension and Breast Cancer Risk in African Women: A Mendelian Randomization and Colocalization Analyses.

    Annals of human genetics·2026
    See all related articles

    Area of Science:

    • Population Genetics
    • Human Genetics
    • Quantitative Genetics

    Background:

    • Previous models of assortative mating often assumed no gene frequency change or one-sided mating.
    • Two-sided assortative mating is more representative of human populations.
    • Human genetic models require analysis of realistic mating patterns.

    Purpose of the Study:

    • To analyze a model of two-sided assortative mating for two autosomal alleles with dominance.
    • To introduce a relative probability of mating variable to account for assortment propensities.
    • To determine conditions for stable polymorphism in human populations under assortative mating.

    Main Methods:

    • Developed a model for two-sided assortative mating with two autosomal alleles and dominance.

    Related Experiment Videos

  • Utilized the concept of relative probability of mating between phenotypes.
  • Analyzed gene frequency dynamics across generations.

    • Main Results:

    • Gene frequencies can vary between generations under two-sided assortative mating.
    • Conditions for the establishment of stable genetic polymorphism were identified.
    • The model's results are dependent on the specific genotypic values assigned.

    Conclusions:

    • The developed model provides a more realistic framework for studying human population genetics.
    • The study offers insights into the maintenance of genetic variation through assortative mating.
    • Further extensions of the model for complex genetic scenarios are possible.