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Flow cytometry related to hematopoietic malignancy
1Department of Oncologic Pathology, Princess Margaret Hospital, Toronto, Ontario, Canada.
Transfusion Science
|November 4, 1995
Abstract:
Flow cytometry is used in the workup of hematological malignancies to establish the immunophenotype of a given malignancy and/or to determine DNA ploidy and S-phase fractions. Flow cytometric data is used as an adjunct to routine morphology and can have diagnostic, confirmatory and prognostic relevance. Samples that can be analyzed include blood, bone marrow, lymph nodes, fine needle aspirates and effusions. DNA analysis can be performed not only on fresh and frozen tissue but also on archival material.