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Updated: Jul 10, 2026

Implantation of Total Artificial Heart in Congenital Heart Disease
Published on: July 18, 2014
Cost-effectiveness analysis of interventions for congenital heart disease
1Section of Clinical Epidemiology, Mayo Clinic, Rochester, Minnesota 55905, USA.
Abstract:
Expansion of the options available for the treatment of congenital heart disease has been accompanied by an increasing realization of the limits of our available health care resources. Cost-effectiveness analysis is one of several analytic approaches that can improve decisions about the appropriate use of technology in interventional pediatric cardiology and other fields. In this article, cost-effectiveness analysis is distinguished from related approaches, such as cost-benefit analysis. Then, basic principles of cost-effectiveness analysis are described. Next, the application of these principles is illustrated, using a recently published comparison of transcatheter versus surgical closure of patent ductus arteriosus. Finally, potential research implications of the surprising findings of this study are discussed.
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