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Updated: Aug 6, 2026

A Protocol to Set Up Needle-Free Connector with Positive Displacement on Central Venous Catheter in Intensive Care Unit
Published on: July 13, 2019
A risk-to-benefit analysis for central venous catheters
J M du Toit1, R Kaftansky, L Wood
1University of Cape Town Leukaemia Centre, Groote Schuur Hospital, Observatory, Cape Town, South Africa.
For cancer patients needing long-term IV therapy, surgical placement of a silastic catheter via the internal jugular vein offers the best outcomes, including fewer infections and longer survival.
Area of Science:
- Oncology
- Vascular Surgery
- Medical Device Technology
Background:
- Reliable venous access is critical for cancer patients requiring long-term intravenous (IV) therapy.
- Various central venous catheters and insertion techniques exist, each with potential benefits and drawbacks.
Purpose of the Study:
- To compare the efficacy and safety of different central venous catheter types and insertion techniques in cancer patients.
- To identify the optimal method for achieving reliable and long-term venous access in this population.
Main Methods:
- Retrospective analysis of 205 central venous catheter placements at a single institution.
- Comparison of different catheter types (e.g., double-lumen silastic) and insertion techniques, including surgical introduction under general anesthesia via the internal jugular vein with an anterior chest wall tunnel.
Main Results:
- Surgical placement of a double-lumen, 12-gauge silastic catheter into the superior vena cava via the internal jugular vein with a 15 cm anterior chest wall tunnel demonstrated the longest patient survival.
- This technique also resulted in the fewest catheter-related infections and high patient acceptability.
- Significant cost savings were observed, particularly in reduced antibiotic usage.
Conclusions:
- Surgical insertion of a specifically designed silastic catheter provides superior outcomes for long-term venous access in cancer patients.
- This method improves patient survival, reduces infection rates, and offers economic benefits through decreased healthcare resource utilization.
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