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Related Experiment Videos

Avoiding double-counting in pharmacoeconomic studies.

M Johannesson1

  • 1Centre for Health Economics, Stockholm School of Economics, Sweden. hemj@hhs.se

Pharmacoeconomics
|April 7, 1997
PubMed
Summary
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Cost-utility analyses can double-count consequences by including them in both costs and quality adjustments. This study explains the double-counting problem and offers solutions for accurate quality-adjusted life year (QALY) assessments.

Area of Science:

  • Health Economics
  • Pharmacoeconomics
  • Decision Analysis

Background:

  • Cost-utility analysis (CUA) is a key method for evaluating pharmaceutical treatments.
  • CUAs measure costs in monetary terms and effects as quality-adjusted life years (QALYs).
  • QALYs incorporate health-related quality of life using weights from 0 (death) to 1 (perfect health).

Purpose of the Study:

  • To outline the potential for double-counting in cost-utility analyses.
  • To identify factors influencing the risk of double-counting.
  • To propose methods for avoiding double-counting in QALY assessments.

Main Methods:

  • The study reviews the principles of cost-utility analysis and QALY construction.
  • It analyzes how financing of healthcare and income losses impacts double-counting.

Related Experiment Videos

  • It examines the effect of question phrasing in quality weight assessments.
  • Main Results:

    • Double-counting can occur when consequences are considered in both cost and QALY calculations.
    • The risk of double-counting is influenced by the financing of healthcare costs and income losses.
    • The phrasing of questions used to assess quality weights is critical.

    Conclusions:

    • Double-counting in CUAs can be avoided by instructing respondents to assume full reimbursement for healthcare costs and income losses.
    • This approach ensures quality weights reflect only health and leisure changes.
    • Other consequences can then be accurately incorporated into the cost estimation.