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Related Experiment Videos

Plateletpheresis: what's new?

A M Valbonesi1, G Florio, V Venturino

  • 1Immunohaematology Service, San Martino University Hospital, Genova, Italy.

Transfusion Science
|November 3, 1996
PubMed
Summary

New thrombocytapheresis devices offer improved platelet collection efficiency and reduced white blood cell contamination. Innovations in apheresis technology enhance patient safety and reduce allogeneic exposures during transfusion events.

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Area of Science:

  • Apheresis technology
  • Hematology
  • Transfusion medicine

Background:

  • Thrombocytapheresis is a critical procedure for collecting platelets.
  • Advancements in apheresis technology aim to improve efficiency and reduce contamination.
  • The year 1995 saw significant developments in cell separation devices.

Purpose of the Study:

  • To review novelties in thrombocytapheresis introduced in 1995.
  • To compare the performance of new apheresis machines.
  • To highlight advancements in platelet and red blood cell collection.

Main Methods:

  • Evaluation of Baxter Amicus CFC and DFC Haemonetics MCS3p systems.
  • Assessment of Dideco Excel and Fresenius AS104 apparatuses for PRBC collection.
  • Analysis of cell separator rejuvenation, including CS3000+ and Fresenius AS204.

Main Results:

  • Baxter Amicus CFC offers efficient platelet collection with low WBC contamination (0.2 x 10^6).
  • DFC Haemonetics MCS3p allows concurrent collection of platelets and plasma-reduced red blood cells (PRBC).
  • Dideco's "Genova" chamber yields high platelet counts with minimal WBC contamination (0.5 x 10^6).

Conclusions:

  • Newer apheresis systems enhance platelet collection efficiency and purity.
  • Concurrent collection of platelets and PRBC reduces allogeneic exposures and associated risks.
  • Technological improvements in apheresis devices contribute to safer and more effective transfusion practices.

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