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Related Experiment Videos

Massive left atrial thrombus: a case report.

F B Saksena, G Kroll, A de Boer

    Cardiology
    |January 1, 1976
    PubMed
    Summary

    A massive left atrial thrombus mimicked mitral stenosis in a patient with aortic and mitral valvular disease. This organized clot may have artifactually lowered left atrial pressure, causing a reversed diastolic mitral valve gradient.

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    Response to: Effect of dose reductions on clinical outcomes, or of outcomes on dose reductions?

    Breast (Edinburgh, Scotland)·2022

    Area of Science:

    • Cardiology
    • Cardiac Surgery
    • Cardiovascular Medicine

    Background:

    • Aortic and mitral valvular disease can present with complex hemodynamic alterations.
    • Left atrial thrombus formation is a known complication, particularly in the setting of valvular pathology.

    Observation:

    • A patient with severe aortic and mitral valvular disease presented with a massive left atrial thrombus.
    • Clinical and echocardiographic findings initially suggested resolution of mitral stenosis.
    • A reversed pan-diastolic mitral valve gradient was observed without evidence of mitral regurgitation.

    Findings:

    • The left atrial thrombus was found to be the cause of the apparent resolution of mitral stenosis.
    • The reversed diastolic mitral valve gradient was likely an artifact caused by the organized thrombus reducing left atrial pressure.
    • This highlights a potential diagnostic challenge in patients with large intracardiac masses.

    Implications:

    • Accurate differentiation between true valvular stenosis and artifactual gradients is crucial for appropriate patient management.
    • The presence of a massive left atrial thrombus necessitates careful evaluation of its hemodynamic impact.
    • This case underscores the importance of considering intracardiac masses as a cause of atypical echocardiographic findings in valvular heart disease.

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