Related Experiment Videos
Vortex pumping for routine cardiac surgery: a comparative study
D R Wheeldon1, D W Bethune, R D Gill
1Papworth Hospital, Cambridge, UK.
Perfusion
|January 1, 1990
Summary
Vortex pumps offer improved blood handling during open-heart surgery compared to roller pumps, showing better platelet preservation and reduced complement activation. Further research is needed to confirm clinical patient outcome benefits.
Area of Science:
- Cardiovascular Surgery
- Biomedical Engineering
- Perfusion Technology
Background:
- Vortex pumps are increasingly considered for arterial pumping in routine open-heart surgery.
- Traditional roller pumps have been the standard, but their impact on blood components is a concern.
- Evaluating novel pumping technologies is crucial for improving patient outcomes in cardiac procedures.
Purpose of the Study:
- To prospectively evaluate the Biomedicus vortex pump against the Stockert roller pump in routine coronary artery surgery.
- To compare the two pump types based on hematological parameters, fluid balance, transfusion needs, complement activation, hemolysis, and microbubble transmission.
Main Methods:
- A prospective randomized study involving 16 patients undergoing coronary artery surgery.
- Patients were randomized into two groups: one using a Stockert roller pump (Group S) and the other a Biomedicus vortex pump (Group B).
- Key outcomes measured included hematology, fluid balance, transfusion requirements, complement activation, hemolysis, and microbubble transmission.
Main Results:
- Group B (vortex pump) demonstrated significant improvements in preserving platelet counts compared to Group S (roller pump).
- Vortex pumping led to decreased complement activation and reduced microbubble transmission.
- While requiring different initiation/termination techniques, the vortex pump's afterload sensitivity posed no practical issues for perfusionists.
Conclusions:
- Vortex pumping appears to offer superior blood handling characteristics for routine open-heart surgery.
- The observed benefits in platelet preservation, complement activation, and microbubble transmission suggest potential advantages.
- Further extensive clinical trials are necessary to determine if these improvements translate into measurable clinical benefits for patients.