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Updated: Jul 28, 2026
A Semi-Automated and Reproducible Biological-Based Method to Quantify Calcium Deposition In Vitro
Published on: June 2, 2022
In vitro evaluation of the calcification behavior of polyurethane biomaterials for cardiovascular applications
B Glasmacher-Seiler1, H Reul, G Rau
1Helmholtz-Institute for Biomedical Engineering, Aachen University of Technology, Germany.
Abstract:
Scope of the study is the calcification behavior of medical grade polyurethanes for cardiovascular devices. Within these applications, implant material calcification is a serious complication. The calcification behavior of these materials is investigated with a dynamic in vitro testing method for evaluating the influence of dynamic mechanical strain and parameters of the solubility of calcium salts.
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