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Phytophotodermatitis from Heracleum mantegazzianum.

E Camm, H W Buck, J C Mitchell

    Contact Dermatitis
    |April 1, 1976
    PubMed
    Summary
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    Exposure to Heracleum mantegazzianum, a giant hogweed plant, caused severe skin reactions in five individuals. Photopatch testing confirmed the plant

    Area of Science:

    • Dermatology
    • Toxicology
    • Botany

    Background:

    • Heracleum mantegazzianum, commonly known as giant hogweed, belongs to the Parsnip family (Umbelliferae).
    • This plant is known to cause phytophotodermatitis, a skin reaction triggered by sunlight exposure after contact with certain plant compounds.

    Purpose of the Study:

    • To report a case series of striate bullous dermatitis following exposure to Heracleum mantegazzianum.
    • To confirm the phototoxic nature of the plant through diagnostic testing.

    Main Methods:

    • Observational case series of five individuals.
    • Clinical assessment of skin reactions.
    • Photopatch testing to confirm phototoxicity.

    Main Results:

    Related Experiment Videos

    • Five individuals developed striate bullous dermatitis within two days of exposure to Heracleum mantegazzianum.
    • Photopatch testing confirmed a phototoxic reaction to the plant.
    • Heracleum species, including H. mantegazzianum, are known producers of linear furanocoumarins.

    Conclusions:

    • Heracleum mantegazzianum can cause significant phototoxic skin reactions (striate bullous dermatitis).
    • Photopatch testing is a valuable tool for diagnosing phytophotodermatitis caused by this plant.
    • The presence of linear furanocoumarins in Heracleum species explains their phototoxic potential.