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Aging: laboratory testing and theories.

L S Gorman1

  • 1Department of Clinical Sciences, University of Kentucky, Lexington 40506-0080, USA.

Clinical Laboratory Science : Journal of the American Society for Medical Technology
|December 9, 1994
PubMed
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Normal aging causes physical changes that alter laboratory test results in elderly patients. Differentiating these age-related changes from disease is crucial to avoid detrimental treatments.

Area of Science:

  • Gerontology
  • Clinical Pathology
  • Biochemistry

Background:

  • Aging is associated with numerous physiological changes.
  • Laboratory test results can be affected by normal aging processes.
  • Distinguishing age-related changes from pathological conditions is challenging.

Purpose of the Study:

  • To review theories of aging.
  • To examine how normal aging impacts laboratory test results in elderly individuals.
  • To highlight the importance of accurate interpretation of these results.

Main Methods:

  • Comprehensive literature review.
  • Analysis of books and published articles on aging, nutrition, and laboratory test interpretation.
  • Focus on studies involving elderly populations.

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Main Results:

  • Normal aging leads to physical alterations that can change laboratory values.
  • These altered results do not necessarily indicate disease in the elderly.
  • Treating "abnormal" results without considering age can be harmful.

Conclusions:

  • The growing elderly population necessitates a better understanding of age-related laboratory changes.
  • Laboratorians must re-evaluate adult reference ranges to differentiate normal aging from disease.
  • Accurate interpretation is key to appropriate healthcare for older adults.