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Hormonal dependency in Darier disease.

P D Espy, S Stone, H W Jolly

|February 11, 1976

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Hormonal changes influence keratosis follicularis (Darier disease) severity. Estrogen excess, seen during pregnancy or with specific oral contraceptives, may lead to skin disorder improvement.

Area of Science:

Dermatology
Endocrinology
Gynecology

Background:

Keratosis follicularis, also known as Darier disease, is a rare genetic skin disorder.
Hormonal fluctuations, particularly those related to the female reproductive cycle, have been anecdotally linked to variations in Darier disease severity.

Keywords:

Biology Clinical Research Contraception Contraceptive Agents, Estrogen--therapeutic use Contraceptive Agents, Female--therapeutic use Contraceptive Agents, Progestin--therapeutic use Contraceptive Agents--therapeutic use Dermatological Effects Ethinyl Estradiol--therapeutic use Ethynodiol Diacetate--therapeutic use Family Planning Mestranol--therapeutic use Norethynodrel--therapeutic use Oral Contraceptives Oral Contraceptives, Combined Physiology Research Methodology