Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Evaluation of five in-line hematocrit monitors.

S Niles1, R Cronbaugh, J Engle

  • 1University of Iowa Hospitals and Clinics, Department of Surgery, Iowa City 52242, USA.

The Journal of Extra-Corporeal Technology
|February 7, 1995
PubMed
Summary

Continuous hematocrit monitoring during cardiopulmonary bypass is crucial. The Cobe device demonstrated superior accuracy compared to four other in-line monitors, showing minimal error over time and varying conditions.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A framework for clinical care pathway renewal: an example from inflammatory bowel disease.

BMC medical research methodology·2025
Same author

Highlight selection of radiochemistry and radiopharmacy developments by editorial board.

EJNMMI radiopharmacy and chemistry·2025
Same author

Anaesthetic subspecialties and sustainable healthcare: a narrative review.

Anaesthesia·2024
Same author

The KMT2A recombinome of acute leukemias in 2023.

Leukemia·2023
Same author

Syncope presenting to the emergency department.

Journal of internal medicine·2021
Same author

Converting gas-driven ventilators from oxygen to air: environmental implications.

Anaesthesia·2020

Area of Science:

  • Biomedical Engineering
  • Medical Device Technology
  • Cardiovascular Surgery

Background:

  • Accurate hematocrit monitoring is vital for effective blood product administration during cardiopulmonary bypass.
  • Existing in-line monitors for continuous hematocrit or hemoglobin require evaluation for clinical reliability.

Purpose of the Study:

  • To assess the accuracy of five different cardiopulmonary bypass in-line monitors.
  • To compare the performance of these devices under varying physiological conditions.

Main Methods:

  • An in vitro circuit primed with human blood was used to evaluate five cardiopulmonary bypass in-line monitors.
  • Hematocrit, blood flow rate, and temperature were randomized to assess device accuracy.
  • Statistical analysis was performed to determine correlations between device error and measured parameters.

Related Experiment Videos

Main Results:

  • Hematocrit significantly correlated with error across all tested devices (p < 0.01).
  • The CDI, Gish, IBC, and MX2 devices showed significant increases in error over time (p < 0.05).
  • The Cobe device exhibited significantly lower overall error compared to other devices (p < 0.001).

Conclusions:

  • The Cobe device is the most accurate for continuous hematocrit monitoring during cardiopulmonary bypass.
  • Device accuracy is influenced by hematocrit, temperature, and blood flow rate.
  • Continuous monitoring with accurate devices can optimize blood product management in cardiac surgery.