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Updated: Jul 30, 2026

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Comprehensive & Cost Effective Laboratory Monitoring of HIV/AIDS: an African Role Model
Published on: October 31, 2010
Model-based evaluation of HIV prevention interventions.
S D Pinkerton1, D R Holtgrave, L C Leviton
1Medical College of Wisconsin, USA.
Evaluation Review
|March 8, 1998
Summary
Mathematical models can estimate infections averted by HIV prevention programs, aiding effectiveness assessments. This study details three risk measures for evaluating HIV interventions and economic efficiency.
Area of Science:
- Public Health
- Epidemiology
- Mathematical Modeling
Background:
- HIV prevention interventions aim to reduce transmission, but direct effectiveness measurement is challenging.
- HIV seroincidence monitoring is often unfeasible for direct intervention impact assessment.
- Mathematical models offer a viable approach to estimate infections averted by interventions.
Purpose of the Study:
- To describe three model-based summary measures of sexually transmitted HIV risk.
- To discuss the relevance of these measures for HIV program evaluation.
- To demonstrate the calculation of these measures in economic efficiency analyses.
Main Methods:
- Utilized mathematical modeling to derive summary measures of HIV risk.
- Applied these measures to previously published data from an HIV prevention intervention.
- Focused on interventions targeting gay men.
Main Results:
- Detailed three distinct model-based summary measures for assessing HIV risk.
- Demonstrated the practical calculation and application of these measures.
- Illustrated their utility in the context of a specific HIV prevention program.
Conclusions:
- Model-based measures provide valuable tools for evaluating HIV prevention intervention effectiveness.
- These measures are relevant for both general program evaluation and economic efficiency analyses.
- The described methods offer a feasible approach when direct seroincidence monitoring is impractical.

