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Preparation of Peripheral Blood Mononuclear Cell Pellets and Plasma from a Single Blood Draw at Clinical Trial Sites for Biomarker Analysis
Published on: March 20, 2021
Computer assisted serum/biological fluid storage: hemophilia serum/plasma bank
M Schaus1, M J Inwood, B O'Keefe
1St. Joseph's Health Centre, London, ON.
Summary
Plasma and serum samples from hemophiliacs are collected for testing and long-term storage. A database computer program efficiently manages sample data, test results, and storage locations for easy retrieval.
Area of Science:
- Hematology
- Biotechnology
- Clinical Diagnostics
Background:
- Hemophilia management requires ongoing monitoring and research.
- Accurate sample handling and data management are crucial for clinical studies.
Purpose of the Study:
- To establish a standardized protocol for collecting, processing, and storing biological samples from hemophiliacs.
- To implement a robust data management system for efficient retrieval of sample information and test results.
Main Methods:
- Blood samples were collected from hemophiliac patients to obtain plasma and serum.
- Samples designated for testing underwent analysis, with results recorded in a database.
- Samples for storage were coded, cryopreserved at -70°C, and their locations logged in the database.
Main Results:
- A comprehensive database was established to track all collected samples.
- Test results and storage locations were readily accessible through the database system.
- The protocol ensured controlled conditions for sample preservation.
Conclusions:
- The implemented system provides efficient management and retrieval of hemophiliac samples and associated data.
- This methodology supports ongoing research and clinical monitoring in hemophilia care.
- Standardized sample handling and data management are vital for hemophilia research.

