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[From malaria to post-transfusional malaria]
1Institut national de la transfusion sanguine, université Pierre et Marie-Curie, Inserm U76, Paris.
Abstract:
Malaria is still a blood transmissible disease, though its frequency is continuously decreasing in non endemic countries. In endemic areas, the number of infected subjects is either stable or increasing, depending on the involved country. Cases of imported malaria, particularly malaria due to Plasmodium falciparum, are increasing in France. In regard to prevention in blood donors, regulations aiming at excluding potentially contaminated donors were implemented with positive effects. Since 1994, no cases of malaria have been reported by the French organization of hemovigilance.
Insights
Malaria, a blood-borne illness, is decreasing globally but increasing in France. Donor screening effectively prevents malaria transmission through blood transfusions, with no reported cases since 1994.
Area of Science:
- Medical Entomology
- Infectious Diseases
- Public Health
Background:
- Malaria remains a significant blood-transmissible disease globally.
- While decreasing in non-endemic regions, malaria incidence is stable or rising in endemic areas.
- Imported malaria cases, especially Plasmodium falciparum, are increasing in France.
Purpose of the Study:
- To evaluate the impact of donor screening regulations on malaria prevention in France.
- To assess the effectiveness of hemovigilance in detecting transfusion-transmitted malaria.
Main Methods:
- Analysis of hemovigilance data in France.
- Review of regulations implemented for blood donor screening.
- Monitoring of malaria case reports in relation to blood donation.
Main Results:
- Implemented regulations for excluding potentially contaminated blood donors have shown positive effects.
- No cases of transfusion-transmitted malaria have been reported by French hemovigilance since 1994.
Conclusions:
- Current blood donor screening protocols are effective in preventing malaria transmission via transfusion in France.
- Hemovigilance systems play a crucial role in monitoring and ensuring blood safety concerning transfusion-transmissible diseases like malaria.