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Survival after radical treatment for transitional cell carcinoma of the bladder
L Daehlin1, S Haukaas, H Maartmann-Moe
1Department of Surgery, University of Bergen, Norway. lars.daehlin@haukeland.no
Aims:
To investigate survival after radical treatment for transitional cell carcinomas of the bladder.
Methods:
This retrospective study included 135 patients with transitional cell carcinoma of the bladder undergoing radical cystectomy or radiotherapy at Haukeland Hospital, Bergen, Norway, during the period 1981-1986. Forty-five patients had cystectomy and 90 underwent external high-dose radiotherapy.
Results:
The overall 5- and 10-year survival rates were 39 and 23%, respectively. After cystectomy 10-year overall survival rates for superficial and muscle-infiltrating tumours were 67 and 26%; after radiotherapy, the corresponding survival rates for superficial and muscle-infiltrating tumours were 26 and 5%, respectively.
Conclusions:
Long-term survival and cure can be achieved after cystectomy in many patients with aggressive superficial or muscle-infiltrating bladder carcinoma. The introduction of orthotopic neobladder reconstruction should encourage the use of cystectomy in patients with aggressive superficial tumour.