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Updated: Aug 11, 2026

Murine Fetal Echocardiography
Published on: February 15, 2013
Magnetic resonance imaging of ductus arteriosus Botalli apertus in adulthood
M Schmidt1, P Theissen, H J Deutsch
1Klinik und Poliklinik für Nuklearmedizin der Universität zu Köln, Cologne, Germany. matthias. schmidt@uni-koeln.de
Insights
Magnetic resonance imaging effectively diagnoses persistent ductus arteriosus (PDA) in adults. This non-invasive imaging also quantifies right ventricular function, aiding treatment decisions for patients with pulmonary hypertension.
Area of Science:
- Cardiovascular Medicine
- Medical Imaging
- Congenital Heart Disease
Background:
- Persistent ductus arteriosus (PDA) is a congenital heart defect typically diagnosed in childhood.
- Diagnostic methods like echocardiography and cardiac catheterization are standard.
- Magnetic resonance imaging (MRI) for adult PDA is infrequently reported.
Observation:
- This study presents four adult cases (3 female, 1 male) of PDA diagnosed using MRI.
- MRI successfully visualized the patent ductus arteriosus in all patients.
- Quantitative data on right ventricular function were obtained via MRI.
Findings:
- Three patients developed pulmonary hypertension and Eisenmenger syndrome, precluding surgical closure.
- One patient without pulmonary hypertension underwent successful surgical PDA closure.
- MRI proved effective in diagnosing PDA and assessing right ventricular function.
Implications:
- MRI is a valuable non-invasive tool for diagnosing adult PDA.
- Serial MRI can monitor right ventricular function in Eisenmenger syndrome patients.
- This monitoring may assist in timing combined heart-lung transplantation.
Abstract:
Ductus arteriosus Botalli apertus is a congenital cardiovascular malformation usually diagnosed in childhood by echocardiography and/or cardiac catheterization. Reports about magnetic resonance imaging of ductus arteriosus Botalli apertus are rare. We report about three adult female patients and one adult male patient in whom magnetic resonance imaging was able to demonstrate the pathology. In all four patients quantitative data about right ventricular function were calculated. Pulmonary hypertension with Eisenmenger syndrome detected by cardiac catheterization had developed in three of the four patients excluding operative closure of the ductus. The patient in whom pulmonary hypertension had not developed underwent successful operative closure of the ductus. Magnetic resonance imaging is a non-invasive tool that can be used for diagnosis of ductus arteriosus Botalli apertus and it allows to quantify right ventricular function. Magnetic resonance imaging can be used repetitively in patients with Eisenmenger syndrome which may be helpful for better timing of combined heart-lung transplantation as ultimate therapeutic strategy because deterioration of right ventricular function can be monitored.
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