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Related Experiment Videos

Developing asymmetric breast tissue.

C W Piccoli1, S A Feig, J P Palazzo

  • 1Department of Radiology, Jefferson Medical College, Philadelphia, PA, USA.

Radiology
|April 6, 1999
PubMed
Summary
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Benign asymmetric breast tissue detected on mammograms can increase in size over time. Pseudoangiomatous stromal hyperplasia is a common finding, suggesting follow-up may be a suitable management option.

Area of Science:

  • Radiology
  • Pathology
  • Breast Imaging

Background:

  • Asymmetric breast tissue on mammography can be a cause for concern.
  • Distinguishing benign from malignant causes is crucial for patient management.

Purpose of the Study:

  • To evaluate the temporal changes in benign asymmetric breast tissue identified mammographically.
  • To determine the histopathological correlation and appropriate management strategies.

Main Methods:

  • Review of serial mammograms in 21 women with mammographically detected asymmetric breast tissue.
  • Correlation with biopsy, ultrasonography (US), and magnetic resonance (MR) imaging findings.
  • Long-term follow-up for patients not undergoing biopsy.

Main Results:

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  • Asymmetric breast tissue size increased in 8 of 21 patients, with a mean size increase of 2.5 cm.
  • Pseudoangiomatous stromal hyperplasia was the common histopathologic finding in biopsy specimens.
  • US and MR imaging were negative for malignancy; no malignancies were reported in followed-up patients.

Conclusions:

  • Pseudoangiomatous stromal hyperplasia is frequently associated with developing asymmetric breast tissue.
  • For benign cases meeting imaging and clinical criteria, follow-up imaging is a viable alternative to biopsy.