Related Experiment Video

Updated: Aug 7, 2026

The Mouse Round-window Approach for Ototoxic Agent Delivery: A Rapid and Reliable Technique for Inducing Cochlear Cell Degeneration
12:21

The Mouse Round-window Approach for Ototoxic Agent Delivery: A Rapid and Reliable Technique for Inducing Cochlear Cell Degeneration

Published on: November 26, 2015

Outpatient management of acute mastoiditis with periosteitis in children

A Niv1, M Nash, J Peiser

  • 1Department of Otolaryngology, Soroka Medical Center, Ben-Gurion University of the Negev, Beer-Sheva, Israel.

International Journal of Pediatric Otorhinolaryngology
|April 6, 1999
PubMed

Insights

Effective outpatient parenteral antibiotic therapy for acute mastoiditis with periosteitis in children is feasible. This approach, involving daily i.m. ceftriaxone and specialist team oversight, achieved a high cure rate with minimal side effects.

Area of Science:

  • Pediatrics
  • Infectious Diseases
  • Otolaryngology

Background:

  • Acute mastoiditis with periosteitis in children typically requires hospitalization and parenteral antibiotics or surgery.
  • There is a need for effective and safe outpatient treatment options to reduce healthcare burdens.

Purpose of the Study:

  • To evaluate the safety and efficacy of outpatient parenteral antibiotic therapy for pediatric acute mastoiditis with periosteitis.
  • To assess the feasibility of managing these patients in an ambulatory setting.

Main Methods:

  • A 36-month study involving 32 children with acute mastoiditis and periosteitis.
  • Treatment included once-daily intramuscular ceftriaxone, wide myringotomy, and daily specialist team visits (otolaryngologist and pediatric infectious disease specialist).
  • Inclusion criteria specified otomicroscopic evidence of acute otitis media, pinna displacement, and retroauricular inflammation.

Main Results:

  • A high overall clinical cure rate of 96.8% was achieved.
  • The mean duration of outpatient treatment was 7 days (range: 4-10 days).
  • Only one child required subsequent mastoidectomy, and no serious adverse events were reported.

Conclusions:

  • Outpatient parenteral antibiotic therapy, managed by a combined otolaryngology and infectious disease specialist team, is a safe and effective strategy for many children with acute mastoiditis and periosteitis.
  • This approach can potentially reduce the need for hospitalization in selected pediatric cases.

More Related Videos

Endaural Endoscopic Atticoantrotomy (Retrograde Mastoidectomy) using a Constant Suction Bone-drilling Technique07:06

Endaural Endoscopic Atticoantrotomy (Retrograde Mastoidectomy) using a Constant Suction Bone-drilling Technique

Published on: May 23, 2021

Endoscopic Cholesteatoma Surgery08:47

Endoscopic Cholesteatoma Surgery

Published on: January 19, 2022

Related Concept Videos

Tonsillitis II: Management01:26

Tonsillitis II: Management

This lesson will focus on the different treatment options for managing tonsillitis, which typically depend on the cause and severity.
Pneumonia IV: Management01:28

Pneumonia IV: Management

The treatment of pneumonia varies based on its severity and the causative pathogen. Here is a structured approach to managing pneumonia, integrating pharmaceutical and supportive care strategies.
Bacterial Pneumonia Treatment
For bacterial pneumonia, antibiotics serve as the cornerstone of therapy. Initial treatment often begins with empirical antibiotics, tailored to the anticipated causative organism and adjusted based on culture results. Key antibiotic choices include:
Endocarditis III: Medical Management01:18

Endocarditis III: Medical Management

Infective endocarditis management involves a multifaceted approach encompassing infection prevention, lifestyle modifications, pharmacological therapy, and surgical management.Infection Prevention:Hand Hygiene: Thorough handwashing is crucial to prevent the spread of infection. Hand hygiene should be performed regularly, especially before and after using the restroom.Oral Hygiene: Good oral hygiene is essential. It includes brushing teeth immediately after waking up and before bed, flossing...
Endocarditis IV: Nursing Management01:29

Endocarditis IV: Nursing Management

Infective endocarditis (IE) is a chronic infection of the heart's endocardium, primarily affecting the heart valves. A detailed nursing assessment for a patient with IE involves collecting subjective and objective data to ensure an accurate diagnosis and timely intervention.Subjective DataThe nurse gathers information about the patient's symptoms and complaints during the subjective assessment. Patients with infective endocarditis often report non-specific symptoms that can mimic other...
Acute Pyelonephritis II: Diagnostic Studies and Management01:28

Acute Pyelonephritis II: Diagnostic Studies and Management

Introduction:For diagnosing acute pyelonephritis, a comprehensive patient history is collected to identify symptoms such as dysuria, frequent or urgent urination, flank pain, or costovertebral angle (CVA) tenderness that may suggest a kidney infection.Physical ExaminationDuring the physical examination, CVA tenderness is assessed. This involves gentle percussion over the costovertebral angle, where tenderness often indicates a kidney infection.Diagnostic TestsUrinalysis: Used to identify white...
Brain Abscess l: Introduction01:26

Brain Abscess l: Introduction

A brain abscess is a focal, intracerebral infection characterized by a localized collection of pus within the brain parenchyma, resulting from microbial invasion and the body’s inflammatory response. It progresses through stages: early and late cerebritis, followed by early and late capsule formation, reflecting tissue destruction, immune response, and eventual encapsulation.Etiology and PathogenesisCausative organisms vary with source and host factors, often involving polymicrobial infections,...