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Related Experiment Videos

[Inhaled corticosteroids and growth].

M Le Bourgeois1, J de Blic, P Scheinmann

  • 1Service de pneumologie et d'allergologie pédiatriques, hôpital Necker, Paris, France.

Archives De Pediatrie : Organe Officiel De La Societe Francaise De Pediatrie
|April 7, 1999
PubMed
Summary

Inhaled corticosteroids (ICS) are effective for asthma but may affect growth. Moderate ICS doses are generally safe for children, with monitoring and proper inhalation techniques recommended.

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Remodelling and inflammation in preschoolers with severe recurrent wheeze and asthma outcome at school age.

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Area of Science:

  • Pediatric Pulmonology
  • Respiratory Medicine
  • Pharmacology

Context:

  • Asthma management in children, including infants, frequently involves inhaled corticosteroids (ICS).
  • Concerns exist regarding the impact of ICS on statural growth in pediatric asthma patients.
  • Asthma itself can independently influence a child's growth trajectory.

Purpose:

  • To evaluate the safety and efficacy of inhaled corticosteroids in pediatric asthma, focusing on statural growth.
  • To clarify the relationship between ICS dosage, asthma severity, and potential growth impairment.
  • To provide guidance on optimal asthma management strategies in children.

Summary:

  • Inhaled corticosteroids effectively reduce airway inflammation in pediatric asthma.
  • Most studies indicate that growth impairment is dose-dependent, with moderate ICS doses considered safe.
  • Monitoring growth and avoiding overtreatment are crucial; alternative therapies or proper inhalation techniques are preferred over high-dose ICS.

Impact:

  • Informed clinical practice regarding ICS use in pediatric asthma.
  • Improved management strategies balancing asthma control and growth monitoring.
  • Reduced concerns about ICS side effects when used appropriately in children.

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