Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Extrinsic allergic alveolitis].

C Delacourt1

  • 1Service de pneumologie et de pathologie professionnelle, centre hospitalier intercommunal de Créteil, France.

Archives De Pediatrie : Organe Officiel De La Societe Francaise De Pediatrie
|April 7, 1999
PubMed
Summary

Extrinsic allergic alveolitis (EAA) is an immune-driven lung condition caused by organic dust exposure. Diagnosis involves identifying exposure, specific antibodies, and lung imaging, with treatment focused on antigen avoidance and corticosteroids.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Impact of prenatal estimation of the risk of respiratory distress in neonates with congenital pulmonary malformations on the choice of delivery site.

Archives de pediatrie : organe officiel de la Societe francaise de pediatrie·2023
Same author

Pediatric hospital care organization: Cross-sectional enquiry in four regions in France.

Archives de pediatrie : organe officiel de la Societe francaise de pediatrie·2021
Same author

Respiratory morbidity in children with congenital heart disease.

Archives de pediatrie : organe officiel de la Societe francaise de pediatrie·2021
Same author

French pediatricians' views on industry-sponsored clinical trials: Toward stronger research on ethics?

Archives de pediatrie : organe officiel de la Societe francaise de pediatrie·2021
Same author

Reopening schools in the context of increasing COVID-19 community transmission: The French experience.

Archives de pediatrie : organe officiel de la Societe francaise de pediatrie·2021
Same author

COVID-19 and schools. Guidelines of the French Pediatric Society.

Archives de pediatrie : organe officiel de la Societe francaise de pediatrie·2020

Area of Science:

  • Pulmonology
  • Immunology
  • Pediatrics

Background:

  • Extrinsic allergic alveolitis (EAA) is an immunologically mediated lung disease.
  • It results from repeated exposure to organic dusts.
  • EAA is typically observed in children around 10 years of age, often with a subacute presentation.

Purpose of the Study:

  • To outline the diagnostic criteria for extrinsic allergic alveolitis in children.
  • To describe the typical clinical presentation and diagnostic methods.
  • To detail the recommended treatment strategies for EAA.

Main Methods:

  • Diagnosis relies on multiple criteria: known exposure, symptom improvement post-exposure cessation, specific precipitins, characteristic imaging (X-ray, CT), and bronchoalveolar lavage findings (CD8+ lymphocytosis).
  • Invasive procedures like lung biopsy and provocation tests are infrequently required.
  • Clinical observation and immunological testing are key.

Main Results:

  • The study identifies key diagnostic indicators for EAA.
  • Subacute presentation is the most common clinical form in pediatric patients.
  • Specific precipitins and CD8+ lymphocytosis in BAL are significant diagnostic markers.

Conclusions:

  • EAA diagnosis in children is achievable through a combination of clinical, immunological, and radiological findings.
  • Prompt identification of the causative antigen and environmental control are crucial.
  • Corticosteroid therapy is effective for acute and subacute EAA forms.

Related Experiment Videos