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Influence of surgical manipulations on hexobarbital effects in rats
Pharmacology
|January 1, 1976
Abstract:
In rats the hexobarbital metabolism is impaired after different surgical procedures leading to muscle damage. This leads to a prolongation of the hexobarbital action. The prolonged effect of hexobarbital in rats with lymphostatic encephalopathy is considered an unspecific consequence of the tissue damage during lymphectomy.