[Tumor angiogenesis]
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Updated: Oct 23, 2026

Monitoring Functionality and Morphology of Vasculature Recruited by Factors Secreted by Fast-growing Tumor-generating Cells
Published on: November 23, 2014
1Istituto per la Ricerca e la Cura del Cancro, Università, Torino. bussol@molinette.unito.it
Abstract:
The formation of new vessels, (angiogenesis) characterizes body development and is pivotal in some diseases. In particular, angiogenesis is crucial for the growth of tumors and metastasis diffusion. The beginning of tumor angiogenesis is caused by the selection of a cancer cell clone which induces an unbalance between inducers and inhibitors of angiogenesis. The inhibition of this process by natural or chemical compounds increases apoptotic index in the tumors, does not causes drug resistance and has been demonstrated to induce cancer dormancy in many animal models.
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