Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Antiphospholipid antibody syndrome].

R Schmidt1, E H Scheuermann, A Viertel

  • 1Medizinische Klinik IV, Johann-Wolfgang-Goethe-Universität, Frankfurt/M.

Medizinische Klinik (Munich, Germany : 1983)
|April 9, 1999
PubMed
Summary

Antiphospholipid antibodies (APA) are linked to thrombosis and fetal loss. Long-term anticoagulation is recommended for symptomatic patients, while treatment for asymptomatic individuals is generally not indicated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

[Adults with congenital heart disease presenting to the emergency department : Potential pitfalls].

Medizinische Klinik, Intensivmedizin und Notfallmedizin·2020
Same author

[Trigger factors for acute TTP].

Hamostaseologie·2020
Same author

Lazy Sundays: role of day of the week and reactivity on objectively measured physical activity in older people.

European review of aging and physical activity : official journal of the European Group for Research into Elderly and Physical Activity·2019
Same author

Heterodimerization of AML1/ETO with CBFβ is required for leukemogenesis but not for myeloproliferation.

Leukemia·2017
Same author

Diagnosis and therapy of coagulation disorders in operative orthopedics.

Der Orthopade·2017
Same author

Prevalence, pathophysiology, diagnosis, and treatment of Willebrand syndrome in orthopedic-trauma patients.

Der Orthopade·2017

Area of Science:

  • Immunology
  • Autoimmunity
  • Hematology

Context:

  • Antiphospholipid antibodies (APA), including lupus anticoagulant (LA) and anticardiolipin antibodies (ACA), are auto-antibodies.
  • Antiphospholipid antibody syndrome (APS) is characterized by thrombosis, fetal loss, and thrombocytopenia.
  • APA can manifest in primary APS (PAPS) or secondary APS (SAPS) associated with other conditions.

Purpose:

  • To define the clinical manifestations and treatment strategies for antiphospholipid antibody syndrome.
  • To differentiate between primary and secondary forms of APS.
  • To guide therapeutic interventions based on patient symptomatology.

Summary:

  • Antiphospholipid antibody syndrome presents with thrombotic events, recurrent fetal loss, and thrombocytopenia.
  • Diverse clinical manifestations are associated with APA, ranging from neurological to cardiovascular complications.
  • Long-term anticoagulation is crucial for patients with thrombosis; prophylactic treatment for asymptomatic individuals is not typically indicated.

Impact:

  • Informs clinical management of antiphospholipid antibody syndrome.
  • Highlights the importance of distinguishing between symptomatic and asymptomatic APA patients for treatment decisions.
  • Contributes to understanding the broad clinical spectrum of antiphospholipid antibodies.

Related Experiment Videos