DFNB20: a novel locus for autosomal recessive, non-syndromal sensorineural hearing loss maps to chromosome 11q25-qter
L Moynihan1, M Houseman, V Newton
1Molecular Medicine Unit, University of Leeds, St James's University Hospital, UK.
European Journal of Human Genetics : EJHG
|April 10, 1999
Abstract:
Autosomal recessive non-syndromal deafness is an extremely heterogeneous condition with at least 19 loci (DFNB1-19) already described. We have used autozygosity mapping to localise a further novel locus, DFNB20, to chromosome 11q25-qter in a consanguineous family originating from Pakistan. A region of homozygosity was observed in affected individuals spanning the interval D11S969-qter.
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