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Related Experiment Videos

Implantable stimulation system dedicated for neural selective stimulation.

S Robin1, M Sawan, M Abdel-Gawad

  • 1Department of Electrical and Computer Engineering, Ecole Polytechnique de Montréal, Canada.

Medical & Biological Engineering & Computing
|April 13, 1999
PubMed
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This study introduces a functional electrical stimulation system for bladder control in spinal cord injury patients. The system enables selective neural stimulation for low-pressure voiding.

Area of Science:

  • Biomedical Engineering
  • Neuroscience
  • Urology

Background:

  • Spinal cord injury often leads to impaired bladder function, necessitating advanced therapeutic solutions.
  • Current management strategies for neurogenic bladder can be invasive or have limited efficacy.
  • Selective neural stimulation offers a promising approach for restoring bladder function.

Purpose of the Study:

  • To present a novel functional electrical stimulation (FES) system for selective neural control of the bladder.
  • To enable low-pressure bladder voiding in spinal cord injured (SCI) patients.
  • To validate a selective stimulation strategy for bladder detrusor and sphincter muscles.

Main Methods:

  • Development of an implantable internal stimulator and an external controller system.

Related Experiment Videos

  • Utilizing radio-frequency electromagnetic coupling for wireless power and operation of the implant.
  • Applying selective high-frequency signals to inhibit sphincter contraction and low-frequency pulses to stimulate the detrusor muscle via S2 nerve stimulation.
  • Physician-controlled software for parameter optimization and external activation via a parallel port interface.
  • Main Results:

    • Acute studies demonstrated the feasibility of the selective neural stimulation strategy.
    • The system allows for external control of stimulation parameters, including frequency and pulse patterns.
    • Successful selective activation of bladder muscles (detrusor) and inhibition of sphincter muscles was achieved in acute studies.

    Conclusions:

    • The presented FES system offers a targeted approach for managing neurogenic bladder dysfunction in SCI patients.
    • Selective neural stimulation via the S2 nerve holds potential for restoring coordinated bladder voiding.
    • Further chronic studies are warranted to confirm long-term efficacy and safety in animal models.