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Related Experiment Videos

A future prediction type artificial heart system.

T Yambe1, N Tanizuka, A Tanaka

  • 1Department of Medical Engineering and Cardiology, Tohoku University, Sendai, Japan. yambe@idac.tohoku.ac.jp, http:/(/)MEC1.idac.tohoku.ac.jp

Artificial Organs
|April 13, 1999
PubMed
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Predicting artificial heart function is crucial for patient quality of life. This study used autonomic nerve signals to forecast cardiac output, enabling better artificial heart control.

Area of Science:

  • Biomedical Engineering
  • Physiology
  • Artificial Organ Technology

Background:

  • Artificial heart systems require precise control to match patient physiological demands and maintain quality of life.
  • Predicting cardiac output is essential for effective artificial heart management.
  • Autonomic nervous system activity influences cardiovascular function and can provide predictive insights.

Purpose of the Study:

  • To predict imminent cardiac output for advanced control of artificial heart systems.
  • To explore the use of autonomic nerve information for predictive control.
  • To develop methods for both short-term and long-term prediction of cardiac output.

Main Methods:

  • Measured sympathetic nerve action potentials and used multiple regression analysis with sympathetic tone, preload, and after-load to predict cardiac output.

Related Experiment Videos

  • Utilized Mayer waves, reflecting sympathetic activity, to develop a mid-term prediction function.
  • Employed Hurst exponent analysis on vagal nerve discharges during positional changes for long-term prediction.

    • Main Results:

    • A prediction function based on sympathetic nerve activity showed significant correlation with measured cardiac output at 2.9 seconds.
    • Mayer wave analysis enabled mid-term prediction of cardiac output.
    • Hurst exponent analysis of vagal nerve activity demonstrated potential for long-term prediction.

    Conclusions:

    • Autonomic nerve information, including sympathetic and vagal activity, can be leveraged for artificial heart predictive control.
    • Short-term prediction is achievable via direct sympathetic potential measurement, while Mayer waves offer mid-term forecasting.
    • Vagal nerve analysis shows promise for long-term prediction, paving the way for comprehensive artificial heart management.