Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

HIV vaccines.

S E Frey1

  • 1Division of Infectious Diseases and Immunology, Saint Louis University Health Sciences Center, Missouri, USA.

Infectious Disease Clinics of North America
|April 13, 1999
PubMed
Summary
This summary is machine-generated.

HIV vaccine development has advanced from basic subunit vaccines to complex multi-subunit and epitope-based vaccines. Future HIV vaccines aim for stronger, longer-lasting immune responses using new technologies and delivery systems.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

The effects of an energy efficiency retrofit on indoor air quality.

Indoor air·2014
Same author

Long-term safety analysis of preventive HIV-1 vaccines evaluated in AIDS vaccine evaluation group NIAID-sponsored Phase I and II clinical trials.

Vaccine·2003
Same author

Bacteremia associated with live attenuated chi8110 Salmonella enterica serovar Typhi ISP1820 in healthy adult volunteers.

Clinical immunology (Orlando, Fla.)·2001
Same author

Measuring injection-site pain associated with vaccine administration in adults: a randomised, double-blind, placebo-controlled clinical trial.

Journal of epidemiology and biostatistics·2001
Same author

Effects of antigen dose and immunization regimens on antibody responses to a cytomegalovirus glycoprotein B subunit vaccine.

The Journal of infectious diseases·1999
Same author

Modulation of immunologic responses to HIV-1MN recombinant gp160 vaccine by dose and schedule of administration. National Institute of Allergy and Infectious Diseases AIDS Vaccine Evaluation Group.

Vaccine·1998

Area of Science:

  • Immunology
  • Vaccinology
  • Infectious Diseases

Background:

  • HIV vaccine development has evolved significantly over time.
  • Early vaccines focused on simple env subunits, while newer generations incorporate multiple subunits and epitopes.

Purpose of the Study:

  • To review the progress and future directions in HIV vaccine development.
  • To highlight advancements in vaccine design, immune response targets, and delivery systems.

Main Methods:

  • Review of historical and current HIV vaccine strategies.
  • Discussion of emerging technologies like adjuvants, naked DNA, and liposomes.
  • Consideration of optimized dosing schedules and vaccine combinations.

Main Results:

Related Experiment Videos

  • Second-generation vaccines broaden immune responses (CMI and Ab) compared to first-generation vaccines.
  • New technologies hold promise for stronger and more durable immune responses.
  • Phase III trials are planned within two years, indicating renewed optimism.

Conclusions:

  • HIV vaccine development is progressing with enhanced strategies.
  • The integration of new technologies and optimized approaches is expected to improve vaccine efficacy.
  • There is significant enthusiasm for the future of HIV vaccine research and development.