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Related Experiment Videos

[RS3PE-syndrome].

S Segerer1, P Dietz-Laukemann, M Schattenkirchner

  • 1Klinikum Innenstadt der Ludwig-Maximilians-Universität, München. Stephan.Segerer@lrz.uni-muenchen.de

Zeitschrift Fur Rheumatologie
|April 13, 1999
PubMed
Summary
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Remitting Seronegative Symmetrical Synovitis with Pitting Edema (RS3PE) syndrome in the elderly typically presents symmetrically. This case highlights an unusual unilateral onset, rapidly resolving with corticosteroid treatment.

Area of Science:

  • Rheumatology
  • Geriatric Medicine
  • Clinical Case Study

Background:

  • Remitting Seronegative Symmetrical Synovitis with Pitting Edema (RS3PE) is a distinct clinical syndrome often seen in elderly patients.
  • RS3PE is characterized by acute, symmetric polysynovitis and pitting edema, typically affecting the hands and feet.
  • The condition generally carries a favorable prognosis and responds well to anti-inflammatory therapies, particularly corticosteroids.

Observation:

  • This report details an atypical presentation of RS3PE in an 81-year-old male.
  • The initial manifestation was predominantly unilateral, affecting the right hand, with suspected axillary vein thrombosis.
  • The patient subsequently developed bilateral pitting edema of the hands and painful movement in both shoulders and wrists.

Findings:

Related Experiment Videos

  • The patient's presentation deviated from the typical symmetric onset of RS3PE.
  • Low-dose corticosteroid therapy was initiated for the inflammatory symptoms and edema.
  • Rapid and significant improvement in edema and inflammatory symptoms was observed following treatment.

Implications:

  • This case expands the understanding of RS3PE's clinical spectrum, including unilateral presentations.
  • It underscores the importance of considering RS3PE even with atypical initial symptoms.
  • The prompt response to corticosteroids reinforces their efficacy in managing RS3PE, regardless of presentation nuances.