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Ewing's sarcoma recurrence vs radiation necrosis in dynamic contrast-enhanced MR imaging: a case report
A M El Khadrawy1, F A Hoffer, W E Reddick
1Department of Diagnostic Imaging, St. Jude Children's Research Hospital, 332 N. Lauderdale, Memphis TN 38105-2794, USA.
Purpose:
We report a case of Ewing's sarcoma in the right distal femur in a 6-year-old male to demonstrate how dynamic contrast-enhanced magnetic resonance imaging (DEMRI) findings predicted histopathology.
Materials And Methods:
DEMRI was performed at presentation and during and after completion of chemotherapy and radiation therapy. Histopathologic studies were done at presentation, at 77 weeks (20 weeks after a pathological fracture), and from the en bloc resection at 104 weeks.
Results:
DEMRI predicted the early tumor response, absence of tumor recurrence, presence of necrosis and lack of fracture healing, confirmed by histopathology.
Conclusion:
DEMRI is a clinically useful tool in managing Ewing's sarcoma.